Any experiences with HIFU localized ablation for prostate cancer?

I had HIFU in 2018 in Charlotte, NC. It was localized. Gleason 3+3, I think. No problems before and none after. PSA went from 4.5 to 0.5. It has inched back up to 1.5, which my uro doctor says is way low. I’m 77. Carolina Urology 704/660-3322 Dr. David Konstandt.

Hey dgbauto,

sorry about the relapse. when did you get the IFU at UC? do you remember your #'s pre -op? Did you have a decipher test pre-op?

hang in.

I HIFU in 2020 and like you PSA went down very low, but creeping back up. PSMA showed PC also spread to seminal vessel. Went to MDAnderson who said they didn’t do HIFU. They did transrectal biopsy without success. Said check psa in 6 months when it more than doubled. They then did transperinial biopsy (which Mayo I read does from beginning) which found Gleason of 9. I had Proton Radiation and Lupron. PSA staying around .03.
Hope my experience helps.

My husband has Gleason 8 localized and we have spoke to the Radiation Doctor and the Surgeon. The RD told us about the process and we have a follow-up meeting with him this week. Last weeks spoke to the Surgeon and he mentioned Surgery or HIFU. That was a little confusing to me because HIFU has not come to play in my research. My husband liked the idea of HIFU instead of surgery/radiation. It is a strong possibility his insurance will not pay for HIFU. However, I have requested a second opinion with another Surgeon at a different institute to get their options. My husband is OK with a second option because if he goes with either options it want happen until the new year. Any thoughts?

I have a friend who has three 4+4 = 8 lesions and just had HIFU done in CT. I warned him that for Gleeson 8's ChatGPT 5 says there is up to a 50% PC recurrence rate. Chat recommended ADT + 25 IMRT sessions + HDR brachytherapy for his clinical profile.

Despite the Chat GPT info...he said he just wanted "one and done". He told me he has to have another MRI in two weeks " to see if they got it all". I am praying for his long term remission

I wouldn't bother responding to someone who didn't post their age, Gleason and PSA Scores.

@kikito1 HIFU has been around for over 20 years. More urologists and Rad Interventionists are offering it in the right cases. Find a HIFU expert and make an appointment. There are other focal therapy modalities available. It all boils down to your staging, tumor location, your individual goals, and your consent to try this option with its issues over reoccurrence. Most insurance pays today, but many HIFU doctors need cash up front because insurance/medicare programs are stingy and not paying enough to the doctor.