I was on Repatha for about 3.5 years with almost no problem except for some mild gastro issues in the beginning which resolved. It lowered my lipid numbers dramatically but my coronary calcium score climbed significantly. However at the 3.5 year mark I contracted bacterial pneumonia which was successfully treated. The problem was that it came back..repeatedly! In fact over the next 1.5 years I had five recurrences. It was only at round 4 that it occurred to me that the Repatha could be the source of the problem so I stopped it in mid-july of this year. I seem to be finally recovering.
Repatha also seems to have increased my blood pressure which has always been historically low with me. Thankfully that is also resolving and my numbers have gone back to normal. All in all a disappointing drug for me especially since my plaque score kept increasing even though my ldl got to 70 or below.