" My Dr said the info that 20-30% of post removal biopsies coming back a higher score is dated and skewed? " My biopsy was 3+4, Prolaris test put me on borderline to treat or watch. Sent biopsy slides to John Hopkins they confirmed 3+4. I went to Mayo, had an MRI, then surgery, and thank God I did. Once my prostate was out and the pathologist could thoroughly examine the whole thing, I was actually 4+3, tertiery 5, cribriform, and perinural invasion. This was in Sept of 2023 so in my case my pathology DID result in a higher score after RALP. I wer as upgraded. Now, maybe your doctor made that statement assuming everyone gets a guided targeted biopsy. However, unfortunatly, Trus random biospies, which I had, because I didn't know any better, are still very common. I don't think Mri guided targeted biopsies had been around long enough to have a RCT's to prove that doctors statement of skewed and dated.