@harry100
A lot of times there are urinary issues and BPH problems when somebody has an enlarged prostate. Sometimes antibiotics can reduce the size, I know cases where it’s come down dramatically after being treated with antibiotics. I would imagine some people just have larger prostate than others, but that could produce more PSA and still be normal.

Frequently a larger prostate will have a higher PSA. As I’ve mentioned, I know somebody who had a really large one and his PSA was 50, but they never found any cancer after multiple biopsies. Unfortunately, he died of a different cancer so I couldn’t ask him how large his prostate was.