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Biopsy Decision

Prostate Cancer | Last Active: 10 hours ago | Replies (22)

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I can’t imagine not getting a biopsy after the MRI spotted a lesion. I couldn’t wait to get in for a biopsy after my MRI showed a lesion. I am probably not the norm but my biopsy was not a big deal. I found it very interesting to see her circle the lesion and tell me she would take 5 samples out of that area and 12 random. 4 of the 5 in the lesion were 4+3 cancer.
I just had a friend who’s urologist suggested waiting after they found a lesion but only a 4.3 PSA. I strongly encouraged him to get a biopsy, especially after my experience and being on this forum for 18 months. He has 3+4 cancer. You want to catch the cancer as early as possible as your treatment options are much more robust. Good luck.

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Replies to "I can’t imagine not getting a biopsy after the MRI spotted a lesion. I couldn’t wait..."

I (70Y) had a slowly rising PSA to 3.8 in Sept 23 and a family history of PC. Got an MRI on the suggestion of my primary care doctor. It showed a small lesion with a PIRAD of 2. Continued to monitor including a free PSA test with a urologist in May 24 that didn't suggest a biopsy. Nov 24 PSA had gone to 6.4. Had another MRI in Jan 25. This time PIRAD 4 and suspected metastases in a lymph node and bone. Biopsy confirmed PC with Gleason 4+4. PSMA Pet in March showed no other involvement. Now on Orgovyx and Xtandi and had radiation. PSA is undetectable and T is 3. Bottom line I followed the guidelines but caught it just a bit late. If I were the OP I would err on the side of getting a biopsy as his original MRI sounds a bit more concerning.