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Anyone had radiation on their central nervous system?

Lung Cancer | Last Active: Nov 25, 2025 | Replies (10)

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@frouke @lls8000 @mamajite Sorry, I should have added more to my post. This is adenocarcinoma spread to my spinal fluid. (It's also about everywhere else in my body, just not causing problems) The radiation will be on my spine and brain. I have the eGFR mutation and was recently on Tagriso. They switched me to a new treatment of Lazertinib and amivantamab a month ago and unfortunately symptoms have progressed although very slowly. I lost the last bit of control of my face that I still had. I'm thinking radiation will be in my near future. My local oncologist called it a last ditch effort. It's not scheduled yet, I just expect it will be soon since I lost some ground since starting the new treatment. I also have an oncologist at Mayo where I go for scans. He's the optimist and I still do my scans at mayo because I don't want to lose him as a doctor.

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Replies to "@frouke @lls8000 @mamajite Sorry, I should have added more to my post. This is adenocarcinoma spread..."

@codym thanks for sharing more about your diagnosis and treatment. I also have EGFR mutated adenocarcinoma. (I have the inherited T790M mutation.) May I ask why they stopped Tagrisso? As I understand it, one of the benefits is that it crosses the blood brain barrier and is helpful for metastases to the brain. I believe @flusshund has had radiation for a brain met and might be able to share about his experience. To offer some hope, my local oncologist gave me about 2 years, 2 years ago. 2 of my 3 primary tumors have completely resolved. Hang on to hope and see the best doctor you can (I vote for Mayo optimist.) Hugs!