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Recently diagnosed stage 1 prostate cancer

Prostate Cancer | Last Active: Nov 21, 2025 | Replies (31)

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Profile picture for rlpostrp @rlpostrp

Your Gleason 6 and PSA 4.87 are the best news, but the Decipher Score says that you have one or more of the 22 prostate cancer-specific genes that will change your course of treatment, and perhaps longevity or probability of recurrence. There are gentlemen who will offer that they are BRCA-2 gene carriers, which changes things quite a bit. I don't know which of the genes are most ominous to carry in your genome - seems that there should be a list of important, highest-risk genes, but I haven't seen one yet. If you were a Decipher of 0.5 or less, you would have much less to worry about, but you clearly have one, likely more than one, genes of concern. Do you have a copy of your Decipher Test report? If not, request it from your urologist or directly from Veracyte Labs in San Diego. They invented the proprietary test...no one else does it but them. My physician didn't think that I need the test, but I insisted. When my urologist did not provide the report to me, I called Veractyte directly. They are EXCEEDINGLY professional and courteous. I had my report 10 minutes after I hung up from the call. The report will detail a lot of things for you. If you do not understand things, it can help you focus on what questions to ask your urologist. You can even call Veracyte Labs back and ask for someone to talk to (they offered me that as well). Good luck to you.

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Replies to "Your Gleason 6 and PSA 4.87 are the best news, but the Decipher Score says that..."

@rlpostrp thank you for your insights. I do Not have a copy of the Decipher test report. It would be very interesting to see what it says specifically so that I could arm myself with intelligent questions for my consult about treatment options.

@rlpostrp
Upon further review of my on line chart I found the full Decipher report by Veracyte labs.
Clinical Stage: T1c, Gleason 3+3, NCCN Risk Category: Very Low/ Low, Decipher Genomic Risk Group: High 0.78

Thanks for giving me the nudge to look further. I had already called the lab but got no answer. Nonetheless, I’m more prepared for my next consult.