← Return to Brachytherapy: What to expect for short and longterm effects?

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@jeffmarc I'm 69, Gleason 4+3, localized, 28cc prostate, no Decipher score as yet. Just had a clean PSMA scan.
It seems that in some analyses HDR-BT monotherapy had competitive results with triple-mode therapy. That seemed attractive to someone not yet decided on ADT. And it is claimed BT delivers a higher dose to the tumor while sparing healthy tissue.

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Replies to "@jeffmarc I'm 69, Gleason 4+3, localized, 28cc prostate, no Decipher score as yet. Just had a..."

@bob1955
People have triplet therapy when they have metastasis outside the prostate. That’s because they cannot be treated by just treating the prostate. Chemo is the third therapy.

Brachytherapy Is designed to treat the prostate not Designed to treat metastasis outside the prostate. In that case they would do IMRT Or SBRT on the metastasis outside of the prostate, if there were not too many.

HDR-BT Is very effective to treat prostate cancer that is isolated the prostate.

@bob1955 The following 2026 article says that SBRT is superior to HDR brachy. Now, I am confused. I always believed that brachy was the best form of radiation. Or was that only applicable to LDR brachy. Search JAMA article with title below.

SBRT vs HDR Brachytherapy for Intermediate-Risk Prostate Cancer
Cristian Udovicich, MBBS1,2,3; Patrick Cheung, MD1,2; William Chu, MD1,2 et al