When I tried ipratropium, an anticholinergic medication, I found it dried me out too much and made airway clearance even more challenging than it already is. A NP prescribed it to me who really was not well versed in treating bronchiectasis and everything that goes with it. It's typically prescribed for asthma and/or COPD, not specifically bronchiectasis. Do you find it drying? Was it prescribed for asthma?

The funny thing about having asthma and bronchiectasis is that there are competing goals. In asthma they want to suppress the cough. In BE they encourage the cough as it's necessary to remove phlegm.

There's a center in Boston that treats bronchiectasis and NTM disease at Mass General. Have you considered seeking treatment there?
https://www.bronchiectasisandntminitiative.org/Find-Care/Care-Center-Network/General-Information
https://www.bronchiectasisandntminitiative.org/Find-Care/Care-Center-Network/Find-a-Center/id/33/massachusetts-general-hospital
Can you say more about what the immune workup found? When I had an immune workup it was found that one of my subclasses was low. Since my immune system is borderline normal, the immunologist hopes that brinsupri (one and only drug FDA approved for bronchiectasis) will help to quell inflammation and therefore infections. We plan to do a trial off of immunoglobulin replacement therapy in 3-6 months once Brinsupri has had a chance to stabilize in my system.