@graybeard46

It has been 7 months since my last 3-month Lupron injection following 44 radiation treatments and I have absolutely no Libido with PSA < 0.1 and Testosterone < 9 for my last two blood tests at 1 month and 4 months ago. I have had almost unbearable side effects that forced me to stop Lupron at 4 months. After 7 months my side effects have tapered just a little, but the serious ones include 24 hour a day sweats that prevent me from even having a sheet to cover me at night plus jock itch, headaches, aching fingers and toes, sore muscles, leg cramps, and brain fog. I am 83 and in good physical shape except for 5 heart bypasses 18 years ago. I exercise vigorously for more than an hour 4 days/week and can outperform anybody over 70 at my gym.

My urologist would prefer that I continue Lupron for 14 more months for my Gleason 4 + 4 cancer but understands the damage Lupron is doing to my quality of life. He thinks my severe side effects may be because I am not a large person (180 pounds) and I had low testosterone even before Lupron.

Reading many articles has led me to believe that the vast majority of men over 80 will have significant side effects from Lupron and poor success in recovering from side effects because many of us already have low testosterone and our system struggles to recover. Maybe dosage level to older men needs to be reduced since low testosterone due to age means overkill by normal Lupron dosage. I do not believe one dosage level is good for all ages and physical body size groups. American pharmacies seem to ignore the physical size of the patient and believe one dose fits all. I think they are very wrong and just do not want to bother with tailoring the dose to the individual's normal testosterone level and physical size.