Unfortunately, though I was treated with ketamine for a year, my CRPS did spread. I had a hard time with the dissociative/hallucinogenic characteristics of this medication. I am taking a break from it right now (haven't had a treatment since January), but don't know whether I will go back. I met a number of patients, however, that did get a great deal of pain relief from these infusions and some of them have been treated with it for many years. My pain doctor and neurologist have both said, if it can't hurt you try it. I am exploring Calmar/Scrambler therapy currently as some chronic pain patients have had good success with this treatment. It is a jungle out there! Best wishes.