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Does anyone have advice on Letrozole?
Breast Cancer | Last Active: Dec 14, 2025 | Replies (56)Comment receiving replies
I’ve been on letrozole for 14 months. I have joint pain, the worse is in my hands, feet, and knees. I also have skin sloughing inside my cheeks occasionally. It’s more annoying than anything. Hot flashes have been moderate and keeping me from sleeping. I’ve found that walking and exercise seems to help a little with the pain. Ibuprofen and my corn bag helps the most. I don’t want to take a chance on my BC coming back, so I’ve decided to continue on. I was afraid to start also and I had my medicine for a month before I started taking it. Stay strong and I pray your side effects are
Minimal.
Replies to "I’ve been on letrozole for 14 months. I have joint pain, the worse is in my..."
@ndozier Wow! so glad to hear that a sister survivor experienced skin sloughing inside their cheeks too! Mine is on the inside of my bottom lip. I was wondering what was going on...even discussed this with my dentist hygienist who suggested a less abrasive toothpaste (I am using Colgate Optic White). I was "wondering" if this was a S/E from the Anastrozole I was on.
So, I am not the only one who had sloughing...never saw this in postings before.
Well, starting Letrozole this Tuesday...will see how this goes!
Thank you all dearly for your positive support! The very best to all!
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@ndozier
OMG thats what Ive done too. I finished radiation and had my rx filled but have been afraid to start it. I wanted to get my energy back first so that I would know if it was the medicine making me tired. Best wishes to you and thank you