I was on the trelegy 100 for quite awhile and it worked great for me....til it didn't..... Now, I can't find anything that works, so they put me on Trelegy 200 (the highest dose they make !!) but they said it has not been approved for copd, well, I tried several other meds and nothing has worked, so I went back on the Trelegy 200 and you know I feel a "(bit)" better, I can at least make it to the kitchen now without nearly collapsing, my Dr. has not given me much guidance to help so I guess I'm on my own...it's frustrating, your Dr. is supposed to know what to do next 😤 I pray for the best for you 🙏