I started treatment for Stage 1, Grade 3 TNBC in early 2023. Finished lumpectomy, chemo, proton radiation. Tumor came back in same location 6 months later. December 2024, I started Keynote 522 chemo and Keytruda and finished in June 2025. I had mastectomy in July. I had to quit Keytruda as it was attacking my gut. The pathology from the surgery suggested the TNBC was gone, but remaining cancer was now ER+. I started on AI Letrozole, but after one month asked to be switched because of terrible side effects (joint pain, bone ache, dry mouth, depression). I will start Exemestane in two weeks instead. I am being treated at Dana Farber in Boston so fairly confident with doctors, but I did ask about the tradeoff of feeling so awful from the AI drugs and what percent it decreased my chances of recurrence. I'm a very young 74, very active and was walking plus lots of yoga throughout my whole treatment. With the Letrozole I could hardly get up and down and started tearing things. My doctor thinks I should be on AI because of my fast recurrence. I'd like to hear other stories and links to research as I'm not sure I want to live with the side effects of AI meds if they do the same as Letrozole. Thank you.