When i was first diagnosed with PMR, my family Dr. prescribed Prednisone...that was November of last year. In January of 2025 i had my first appointment with a Rheumatologist and before I saw him i had bloodwork done. After 2 months on Prednisone my inflammation and pain was no better and so he put me on Dexamethasone along with Rinvoq...made progress until i started to taper off and pain and inflammation would come back..at times it seemed worse. After 2 months of Rinvoq, he switched me to methotrexate on the weekends...nasty stuff. as of today and about a year later I'm on 1/2 pill of dexamethasone as needed and a once weekly injection of Tyenne (tocilizumab-aazg). At this point i feel like the pain will always be there and depression of sorts has set in....good luck