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Tymlos blood pressure side effects etc. very nervous! Help…
Osteoporosis & Bone Health | Last Active: Nov 29, 2025 | Replies (53)Comment receiving replies
Thank you to you both. I am suppose to start for the first time Thursday night (11-13-tomorrow)
When I asked Tymlos and my doctor they both said not to
“lower the dose by listening for the clicks when you turn the dial. Each click is 10mcg of PTH 1-34.”
I am not sure why. Many other drugs allow to start slow and acclimate except antibiotics some pain meds etc.
There does not seem to be any published safety guidance on this approach…it sure seems like it would be easier. Hoping to hear from the “Tymlos Nurse” today and or speak with the specialty pharmacy before I start.
Thank you for taking the time to respond.
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@osteopatient2026 Sending you my best today. 🌺 I’ve read here that women do experience success and relief by titrating down if the side effects become too uncomfortable, as well as starting at a low dose and titrating up as side effects are better tolerated.
It just makes perfect sense to me to give those parathyroid glands a gentle nudge by starting low and moving up as your body adjusts.
Why put the meds in a titrating pen if we can’t do that?
Personally, I think there’d be a higher rate of success if we were able to maintain control over the dosage, so long as we commit to getting to the 80 mg dose for optimum results. We all WANT the medicine to work, for heaven’s sake, right?
If no study has been done on titration, I’d honestly wonder why (though we’re smart cookies. We know why.)