@lizzyj58 Hi. You might ask your husband's treatment team if they plan on 3 biweekly 100 mg cisplatin chemotherapy treatments. And if so, why not weekly 40 mg cisplatin treatments. I had the latter. The side effects are significantly less with the weekly lower dose treatment. The research suggests that the key in the chemotherapy's success is to get to a minimum of 200 total mg. If he can tolerate more, then that is better.

My chemo made me nauseous but was completely controlled through antiemetics. I was also very fatigued which got worse over time.

Hi @lizzyj58,

I saw this mentioned yesterday in a different thread and thought I would pass it along in case you didn't see it.

jfh1970 | @jfh1970 | 3 hours ago
In reply to @justwow "@jfh1970 Thank you so much. I’m just wondering why they are recommending that I do the..." + (show)
@justwow The Mayo team believed the metastasis to my left lymph nodes were too extensive to risk surgery. Plus most surgeries end up needing radiation chemotherapy anyway. HPV+ SCC is very susceptible to radiation.
Ask the team if their institution is participating in the DART 2.0 trial, which tracks the DNA marker of the cancer cell death. Mine dropped to zero by week 4 and I was able to stop a week later (two weeks early - meaning fewer and less severe side effects).

@lizzyj58 my chemo was cisplatin. Its taken once a week during radiation. I had little trouble with it. Evidently nausea is the biggest problem with it. I was never nauseous from it.