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Profile picture for alfalfa52 @alfalfa52

2 months after starting Skyrizi for psoriasis I developed sever cellulitis, fever, chills, and exhaustion. Resolved after 14 days of Augmentin. FYI: very health 65yo with no previous hx of cellulitis. The same scenario repeated every 4-5 weeks and treated with different antibiotics for the next 8 months. Dermatology did not think Skyrizi was the cause. After seeing 3 different specialists, who all admitted they had seen nothing like it and did not have a clue, I stopped Skyrizi after 6 months. Finally saw an Infectious Disease doc who put me on chronic low dose antibiotic for 3 months as preventative while Skyrizi slowly worked its way out of my system. Now antibiotic and infection free for 6 weeks with fingers crossed.
Can't prove Skyrizi was the cause but after 6 severe infections in 8 months baffling the experts I would advise extreme caution.
Other than the AbbVie who, considering their advertising budget, I doubt would listen is there somewhere I can report this?

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Replies to "2 months after starting Skyrizi for psoriasis I developed sever cellulitis, fever, chills, and exhaustion. Resolved..."

@alfalfa52 I also have psoriasis, but I choose not to take Skyrizi due to its known side effects.
Read: https://www.skyrizi.com/psoriasis-psoriatic-arthritis/about-skyrizi/side-effects-and-safety

@alfalfa52 I don’t have words for what you went through. I’m so sorry, and truly hope you are well on the road to a long, healthy recovery. Has your psoriasis been in remission?

Though I take it for psoriatic arthritis, and your story and infections are definitely more serious than mine, I am angry that no one thinks the drug caused this. Like me, you were healthy (and cellulitis-free) prior to taking SKYRIZI. Those 6 severe infections in 8 months weren’t happenstance, and it’s both ridiculous and insulting for anyone to suggest so. And I keep being told the same thing!

One thing that been irritating me is how on the SKYRIZI site, as well as a lot of medical journals/articles, there’s never a full accounting of side effects or anecdotes like these. I know that for a lot of people, it’s been a miracle drug. People are living their best lives while on it, and I think that’s wonderful. But stories always have two sides.

Last week, I spoke with my ambassador, and while she sympathized with me (I gave her a full accounting of my issues), all she really wanted to know is when I planned on ordering my next dose, and if I had a problem ordering it.

It’s almost like the drug is being, I don’t know, protected somehow. It’s weird to say, I know.

I’m at the 7 month mark myself, and honestly, my body hurts more on the inside now than before I began taking SKYRIZI.

Thank you for your reply, @alfalfa52. I am sending healing thoughts your way.