@peterose
Hi…Yes…I take Linaclotide…the Rx name is Linzess. I take the highest dose…290 mg. I started off at the lowest dose …75 mg…no effect at all. The highest dose doesn’t really do too much…it is not a laxative. It is taken in the a.m. 30 min. before breakfast…needs to be taken on an empty stomach. It definitely does not interact well with food. I tried taking it before dinner….oooo not good…very bad belly cramping . Recently I was only having a protein shake for breakfast so I took the Linzess with that…ooooo not good….bad belly cramping all day. Take as directed…you may want to give it a try. It takes a month or so to tell if it’s helping….maybe give it a 90-day try. Senna-S tablets may be helpful… senna is the natural stimulant laxative and the -S stands for stool softener. Easy to take, recommended by my PCP. I also drink a hot Smooth Move tea once in a while…it is senna leaves ..again, a natural laxative. Doesn’t taste that great…but if it helps, it is worth taking now and then. Hope this info helps a bit. 🙂💖