Hi @jrm78, welcome to Connect! I am sorry you are having problems, sounding like Repatha may be the culprit. It is important to pay attention to when you take shots and when you have breathing problems. You may find a connection, and if so it may be sneaky. It is a good thing you are checking with your cardiologist and pulmonologist to make sure something else isn’t going on. I understand why you consider Repatha as the cause because of the timing of when you started having problems.

Like you, I found the drug company that makes Repatha to be less than helpful. My experience was that the night following injection #9 I abruptly woke and sat straight up in bed thinking I had forgotten to breathe.

I searched “Repatha breathing” from the home page and found discussions and comments you may find helpful, if you have not reviewed already.
https://connect.mayoclinic.org/search/
You mention having more testing coming up. I am interested to know what you find out and hope you come back and provide and update.

Do you plan to continue Repatha?