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Osteoporosis & Bone Health | Last Active: Nov 19 3:41pm | Replies (26)
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Replies to "@mayblin Yes, we're definitely leaning towards teriparatide at this point. I'll cross that exercise off the..."
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@njx58
I’ve come across a few cases of PTH + HRT, but don't know how to read into the results. There is a published clinical study of teriparatide + HRT if you’re interested:
https://academic.oup.com/jbmr/article-abstract/16/5/925/7516026
To me, it’s hard to draw firm conclusions on the role of HRT in combination with teriparatide because the study didn’t include a teriparatide-only arm. In addition, the study investigated PTH added to established HRT, and the teriparatide dose was slightly higher (25 mcg), given for a longer duration (3 years) than the standard regimen. All these factors influence end results.
If the topic of HRT + PTH comes up, I’d ask the physician for supporting data/references.
If baseline btm indicates a low turnover state, I wouldn't throw HRT in the mix if I were the patient.
None of my care team physicians are particularly keen on checking hormone levels, although I insisted on a baseline, which was within the expected range. For follow-up, we mainly rely yearly DXA scans (or earlier if needed), and monitoring bone markers. I did a course of Forteo and followed with HRT as maintenence btw.