@njx58, if your wife decides to add weights to her routine, she might want to see a PT trained in osteoporosis. Mayblin's caution about extension and flexion is really important. Just picking the weights up off the floor could become a life changing event.
Vertebral osteoporosis is actually multiple fractures without compression. https://www.researchgate.net/figure/Light-microscopic-views-of-normal-left-and-osteoporotic-right-cancellous-bone_fig3_230657347
Dxa warns a person that they have bone missing and because weight bearing exercise is good for bone we are advised to add weight to an already fragile structure before reinforcing the structure. not even giving the bone the possibility of restructuring itself. It is good to have strong muscle surrounding the bone, but the muscle may already be stronger than the bone at this point. I'd wait the weights. I stopped weights. back bends, crunches, anything bending forward. Even bending forward in a chair had to wait for Forteo to provide bone to the missing structure.
I'm a long time runner and don't think it wise to stop or even lessen the running routine. If possible, though, running on soft turf instead of cement or asphalt would be protective.
If she does decide to let you start her on weights, light weights. Be sure that it is her decision. She might look at https://www.youtube.com/watch
Of course, now that your healthy bones are doing alllll the lifting, vacuuming, (bending) making the bed, grocery shopping careful light weights might be necessary for her to get sufficient exercise.