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@sriddle1

Yes, unfortunately no test shows what is really going on with 100% certainty but knowing that a test is just 40% accurate is really disheartening. PSMA also can show false positives which is also very concerning since false positive can cause unnecessary treatments or over-treatment. Only full examination of removed gland shows actual status of the PC but still not 100%. There could be some micro metastatic clumps of cells that escaped the gland and there is no way to know IF they escaped or WHERE they went. That is why even patients with low gleaoson score and perfect margins still sometimes develop BCR down the road.

You mentioned that you are "stuck on staging" and it is completely understandable - one tries to grasp the extent and meaning of it all and is looking for any positive detail in avalanche of information that was thrown at you. I remember reading 30 scientific papers with average of 10 pages each and than holding onto one single sentence that showed some "positive" data that gave me some hope - we do what we can to stay sane and strong.

You are doing great < 3 . In a very short span of time you learned a lot and managed to be excellent advocate for you partner ! I am sure that he will now get super care and correct PC treatment with your help and will have great results in the end : )

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Replies to "@sriddle1 Yes, unfortunately no test shows what is really going on with 100% certainty but knowing..."

First, we are with you! This group is incredibly supportive. I too post for my husband. He rarely talks about what is going on. He is Gleason 9 which has broken thru the capsule and the cancer is in his seminal vesicles, but no lymph nodes. The urologist after the biopsy would not consider surgery so we just finished a course of radiation, abiraterone + predisone and Zytiga. It is not easy on anyone - you or your husband. Everyone patient is different but it is good to share info. We go to the doctor every 3 months for the same reason: to see if the PSA has elevated. My husband does not like to talk about any of it, and defers to me at the oncologist appointments. It’s ok. I don’t mind at all. So we are on careful watch. With you and your hubby!