@jeffmarc I had a turp as a young man and wish I would have had sought a 2nd opinion. Anyway, it ruined my sex life and I haven't had sex with my wife for 3 years because I can't get an erection. I have started down the trimix road and the first batch did nothing so he bumped me up to 20/40/2 strength of alprostadil/papaverine/phentolamine)/ml. Of course I am in the 20% who reacts to alprostadil and get aching dick disease (ADD). The stuff is also not working yet. I injected 70 units last night and my unit was pretty full and firm but not pointing the sky so it is hard enough to penetrate my wife's vagina. I am very frustrated and not sure I am going to get there. Anyway, thank you for raising this informaton that i saw on another trimix discussion yesterday. I just asked my Urologist to give me the highest dose of low alprostadil formulation Trimix #12 (10mcg/30mg/4mg) /mL. Do you know if they can go higher like 10/40/8? Maybe bimix would work but who knows. I just want to get hard enough have sex with my wife. I have been so frustrated and embarrassed.