I had grade 2 IDC. Did lumpectomy. Initially they said only radiation and ai therapy but then also positive oncotype so chemo was discussed. Initially radiologist went over findings because had the appointment scheduled before results came in. She indicated it would give me 17-20% decrease in distant metastasis. Then discussed with oncologist and said about the same. I also struggled with the decision. My brother found an article that indicated the oncotype test was the number 1 reason for unneeded chemo. But this is so rock vs hard place because if I decided against it and then they found mets a couple years later, too late for a redo. I decided to go ahead and had the same - 4 rounds of Taxotere and cytoxan. They never discussed cold caps/gloves/boots (or I just missed it - doing this by myself and it was all a rush it’s possible) so didn’t do any of that. I lost hair but it did grow back, just thinner (but that could be the ai therapy as well). My blood counts have not yet normalized but he said could take 2-3 years. For me, the only long term so far is my mouth. Did get the ulcers and swelling that was a possible side effect and my teeth moved. I had several teeth break, fillings loosened now have chronic periodontal disease that they’re trying to control so cleanings every 3 months. While I think it aged me, nothing else major so would I do it with what I now know? Yes, I think I would because of that decrease in possible mets make me psychologically better.