I take Trulance (prescription) daily and Miralax at night and one VSL3 probiotic daily..try not to eat fried foods or much dairy.. 2 plant based Vanilla Ensures daily and one Thomas multigrain English muffin (8 gr fiber) with plant butter.. I avoid sucralose if at all possible..drink as much water as you can stand.. I tried Amtiza and Linzess and neither one worked.. the Trulance has really helped ..I hope you get relief!!