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Bone turnover markers (CTX and P1NP): do you have a baseline?
Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (270)Comment receiving replies
I am taking eivinity romosozumab injections for 6 months now. 6 more months to go. Taking Calcium 1,200, Vitamin D 5,000 IU
I also took Biotin 100 tablets but I stopped 1 week before blood test. Did the Biotin affected my PINP & CTX reading ?
Before - PINP=92, CTX = 532
After 6 months - PINP=132, CTX = 806
Replies to "I am taking eivinity romosozumab injections for 6 months now. 6 more months to go. Taking..."
@alit
I agree with @gently, your CTX results is a bit unusual for someone on Evenity. Usually, CTX goes down below baseline while on treatment and doesn’t rise above it until after the therapy ends.
Timing of lab, fasting status, even which lab was used can affect the results. Other factors, like recently stopping Prolia, healing from a fracture, or having had (bone) surgery, etc., can also affect CTX.
@alit - did you also stop any of your other supplements before the blood lab? I take the same amount of calcium & Vit D as you do while on Evenity injections for 5-mo so far
@alit
58-f002/https://pmc.ncbi.nlm.nih.gov/articles/PMC12072299/figure/jcm-14-02
Will your doctor weigh in on these markers?
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@alit did any of you took serum PTH test before sarting any medication??....most of the time paratahyroid gland is the culprit for overproduction of pth harmone which in turm cause osteopososis and if that is the cause of ostoeporosis then taking hRT injections can do more harm than good...it might lead to more bone loss