I have been reading through the thread from the beginning. It contains a lot of helpful info. Thank you all who have contributed to it. Everyone's contribution is helpful. Update here is that my Endocrinologist( even though he said he did not believe it was necessary) was willing to support my request for a CTX and P1np testing schedule of now in October again at 6 weeks and again before I see him in January . Of this I am thankful. My first P1NP was a 33mcg/l and CTX at 225pg/ml. Doing the conversion I believe I had a ratio of 146.66. I don't really understand what that means. I saw in one paper the desire to have the P1NP below 30. If anyone can give me more info and research about this I would appreciate it.