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PSA levels at 4.3 to 4.8

Prostate Cancer | Last Active: 7 hours ago | Replies (16)

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@heavyphil
Thank you for your advice and help.
Here is the extract from my PSMA PET scan result today and what this SUV 4.6 in prostate Gland means?
EXAM: PSMA PET/CT VERTEX TO DISTAL THIGH
HISTORY
: Initial treatment. 66 year old male with C61 malignant neoplasm of prostate, unfavorable intermediate risk. Staging prior to treatment.. PSA up to 4.9.
PET/CT REQUESTED FOR
: Initial treatment strategy.
RADIOPHARMACEUTICAL
: 9.9 mCi F18 DCFPyL IV (PSMA)
TECHNIQUE
: This is a combined PET/CT scan. PET is performed from top of skull to knees after a 62 minute uptake phase. CT is performed without oral or IV contrast.
Physiological distribution of tracer is seen within the salivary glands and lacrimal glands, blood pool, liver, spleen, pancreas, ganglia, bone marrow, bowel, kidneys and urinary tract.

SUV reference:
SUV max parotid/salivary glands: 18.1
SUV max right hepatic lobe: 9.3
SUV max descending thoracic aorta: 1.3

PSMA - expression score:
High (3) SUV parotid/salivary glands
Intermediate (2) SUV liver
Low (1) SUV blood pool

THORAX: No increased uptake in the lungs or mediastinum. No suspicious pulmonary nodules. No pleural or pericardial effusions.
ABDOMEN/PELVIS:
Evaluation of prostate bed: There is a focus of abnormal uptake with maximum SUV of 4.6 in the posterolateral right lobe (slice 279) at the mid gland level. No involvement of the seminal vesicles.
Evaluation of lymph nodes: No increased uptake in pelvic, retroperitoneal, or abdominal nodes.
No increased uptake in the liver or spleen. Liver and spleen are not enlarged. No hydronephrosis. No adrenal nodules. Pancreas is unremarkable.
BONES/BONE MARROW: No increased uptake in the skeleton and no suspicious lytic or blastic lesions.

IMPRESSION:
1. PSMA avid malignancy in the right lobe of the prostate as above. No evidence for extraprostatic disease.

Thank you for the opportunity to participate in the care of this patient.

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Replies to "@heavyphil Thank you for your advice and help. Here is the extract from my PSMA PET..."

@cadman2025 It looks like all the cancer is localized in the gland…VERY good news!
Now the Decipher score will show if ADT is needed if you choose radiation of any kind. Intermediate unfavorable may still not need ADT if all the cancer cells can be eliminated.
If you opt for surgery - and the pathology remains the same - you just might be done. However, if the path is upgraded to more aggressive, or cells are found in the lymph glands ( regardless of low SUV) you ‘may’ need additional treatment in the future.
I’m not a medical doctor and certainly not an oncologist, but it seems from a layman's POV that your PET scan looks better than you feared. The cancer is definitely there, but very treatable…Best,
Phil