Received the news on Halloween. I have prostate cancer. Need advice.

Posted by frank1956 @frank1956, Nov 1 7:26pm

I previously had 2 benign biopsies in 2024. Urologist/Oncologist asked to follow up in a year. So on September 2025, I did PSA (5.4) and MRI (2 legions PI-RADS3, and PI-RADS4). These 2 legions are similar in size with the previous 2 MRI's from 2024.
Doctor ordered a biopsy. On Halloween day, the report came and it shows out of 18 cores, there are 2 Gleason 6, and 1 Gleason 7 (3+4), which is with 40% core, and G4 is 10%.
I am scheduled to see my Urologist/Oncologist on Wednesday. I will ask for a Decipher or Polaris test and a PSMA scan. Maybe a genetic test to check BRCA1, BRCA2 genes?
I am not sure what else to ask from the doctor. Any advice will be greatly appreciated.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Lots of great advice. Let me add two more thoughts for you.

One if you don't have it get Dr. John Walsh's book on "How to Survive Prostate Cancer", get the 5th edition. You will learn everything you need to know.

Two, consider a plant based diet, away from dairy and animal fats. Not conclusive but seems to reduce the spread of prostate cancer.

Best wishes on your journey.

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Someone recommended this boat to me, and I found a very helpful: Dr. Patrick Walsh’s Guide to Surviving Prostate Cancer.

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I'm a fit 74 year old. I had the same (3+4) Gleason score as you on my second biopsy, a year after the first 3+3. I ultimately decided to have radiation treatment, but the reasoning is possibly useful to you. Yes, I could have continued Active Surveillance, but we already see that the cancer is growing, even if it's not high risk. The doc said he could not endlessly do biopsies. I had a Decipher test (highly recommended) that showed relatively low risk and no need for hormone therapy, but still...how long do you want this growing within you? That's a question every man needs to answer for himself. What I found is all the tests and medical appointments were very stressful and it was affecting my mental health and my partner's. I decided let's treat this now rather than later and try to move on with life.

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Depends on where the tumor(s) are located. If near the colon wall I would not just sit there and watch as that is a danger zone. Once in the colon, things become more difficult. If central, then maybe a wait and watch, but I can assure you that your gleason scores will change. I would undergo a a URONAV biopsy for precise location.
My second biopsy cancer cells were missed entirely until the a guided URONAV was performed.

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I'm sorry to hear the news, but it sounds like it was found in early stages, so be grateful for that. There are lots of folks in this group with lots of experience and opinions, which helps, but I also recommend a book that gives lot of great advice based on actual clinical trials and studies: Dr. Patrick Walsh's Guide to Surviving Prostate Cancer. Be sure to get the 5th edition, which came out this year, not the first, which was around 2001. I wish I had read the book before my surgery; I would still have had the surgery, but would have been much better informed about the decision, and about what was yet to come post surgery. Best of luck to you.

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First, don't panic but get your prostate treated either surgery, radiation, or both whichever you and your doctor agree. My nonprofessional advice is the sooner you get it treated the better. Watchful waiting will only give the cancer time to spread. You do not want that.

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It appears that you like a lot of us have caught this early and you can make some decisions once the PSMA comes back. I hope your PSMA comes back as no spread. To be honest with you I cried like a baby when the Urologist told me there was no spread and mine was caught early. Other than what's been suggested, ask your Urologist lots of questions about the PSMA and the other tests that you are about to get. You aren't alone in this, and this forum is fantastic. Take it one day at a time, somedays it will be a struggle. Don't dwell on your diagnosis and if you can find ways to distract your brain from overthinking this. A great deal of on here are living proof that early detection is the key. We are all here for you! 🙂

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Profile picture for fbt217 @fbt217

After you see your current doctor get at least a second opinion, preferably at a top level hospital like Mayo, Anderson or MSK.
Then talk to as many men, who have gone through this, to get an idea of what is ahead.
Then decide what suits you best.
Good luck.

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@fbt217
I agree that the second opinion and treatment should be at a top-level hospital. But you may want to consider that all doctors are not the same. In my opinion, the selection of a doctor, at a top-level hospital, is just as important.
Good luck!

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Frank,
take a deep breath. You have time to decide for yourself the treatment plan you want to do. You are your best advocate. My initial scores were about the same as your, done at my local Dr. After reading Walsh's book I decided to go to Mayo in Rochester, MN and have them look at the slides and the scores were higher so waiting was off the table. I decided that radiation was the route for me so we set it up and the "team" at Mayo could not have been better nor my decision for radiation. I did 5 rounds, stayed at their facility for cancer treatments and as one guy said as he was leaving the facility"this was the best worst time of my life." 6 months post treatment my PSA was 2.2 and now 12 months post treatment it is .78. Dr Rajkumar is often in my thoughts for her compassion and attitude plus she is one smart Dr. Good luck to you.

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