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← Return to CA 19-9 high but no malignancy
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CA 19-9 high but no malignancy
Pancreatic Cancer | Last Active: Nov 14, 2025 | Replies (23)Comment receiving replies
This is so helpful to me. Thank you. I had a Whipple in March 2025, and successful removal of my pancreatic tumor. Following surgery, though, my CA 19-9 levels were higher than they'd been, and have kept climbing. Current reading is 196 -- much lower than your mom's; but the trajectory has been steadily upward, even while on a regimen of gemcitabine, and now a new regimen: 5F-U with irinotecan. Based on your post, I've just checked my B-Complex vitamins, and noted that Biotin is included. So I'll definitely be checking what happens if I d/c that one vitamin. Very grateful to have your posting about this. It may not make a difference in my case, as my two Signatera tests since surgery registered "abnormal" results (though the second was lower than the first), but it's tremendous to have something to try here. Like your mom, I'm basically feeling well and doing well, so the CA 19-9 rise has been baffling -- especially in the absence of radiological evidence of disease. All the best to you and your mom!
nbcesq
Replies to "@edios1 This is so helpful to me. Thank you. I had a Whipple in March 2025,..."
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@nbcesq I don't want to be a wet blanket or bearer of bad news but climbing CA19-9 levels should be watched. In March 2025, my husband's PET scan showed no evidence of disease but the CA19-9 levels climbed slowly from normal to 40s and then 70s even with Gem-Abraxane. The onco continued with chemo and scans. In a PET scan in May, the cancer showed up. Sometimes the cancer is so 'small' that it cannot be picked up in a scan. I hope for yours it's the supplements but just keep an eye on things. All the best.