@sueinmn my Pulmonologist at Mayo Jax had me taking Azrithromycin 250mg daily from mid January 2025 thru mid September. On September 5, I started the new medication for Bronchiectasis Brinsupri, so my Pulmonologist recommended I wean off the Azrithromycin, first every other day for two weeks then 3 days a week for one week, then nine. He also stated that he did not think that the Azrithromycin would add anything else to help, since I’m taking Brinsupri now. But he did say that if I feel that I’m having a setback (as he called it) to go back on Azrithromycin daily and notify him. As we all know Azrithromycin is an antibiotic, and I know he/we have to be cautious of building up resistance to the antibiotic’s. It has and did affect my hearing, I had tubes out in both ears in July, and I’m scheduled to see a Mayo Jax ENT in January.