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Today’s (10/30/25) psa test

Prostate Cancer | Last Active: Nov 1, 2025 | Replies (29)

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@johndavis60
Are you on hormone therapy? Being on it makes difference in PSA. From your post you had radiation not RP. So your PSA is excellent. I wish mine was that low but my lab won't give numbers below .10 At my lab below .10 is considered undetectable

Depending on your lab they determine what is undetectable number. How long has it been since your radiation ended? I hope you were briefed that PSA will bump up and down and is to be expected (per my UFHPTI R/O and Mayo/RO, PCP Mayo). Completely normal and to be expected.

It is the steady rise over time that is a concern not an occasional bump up and down. I was told to expect the bumps and have had two of them in 2.5 years. I am at PSA now of .12 That per my R/Os is excellent. I did not have hormone treatment before, during, after. My R/O at UFHPTI said goal was to have it stay below 1.

Many things can affect PSA levels and not indicate cancer back or growing. I was told by my R/O you could have different PSA level of a lab from one test to another using same blood.

At Mayo Jacksonville a PSA below .10 is considered undetectable. You will not get a number below .10 from Mayo Jacksonville lab. It will just have the symbol below .10 Other labs will have different numbers for undetectable. I am not sure why some go so far down and others do not. I would expect types of devices used but not a medical professional and just an opinion.

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Replies to "@johndavis60 Are you on hormone therapy? Being on it makes difference in PSA. From your post..."

@jc76 I had a prostatectomy in May 2025. I am now doing Firmagon as of Aug 6, abiraterone as of Sept 11, and radiation. I have 6 out of 38 radiation treatments to go. I get nervous about my psa because I am Gleason 9, idcp, cribriform with tp53, pten loss mutations, somatic not genomic. I have to be aggressive as possible.
Thanks -John 😉