@pesquallie, I noticed that you wished to post a URL to a Mayo Clinic News Network article with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe. Allow me to post it for you.

Here is the link to the news story:
- Study Solves Testosterone’s Paradoxical Effects in Prostate Cancer https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer

And to the actual study:
- Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells https://www.nature.com/articles/s41467-024-52032-y

I have to disagree with the statement about doctors not embracing advancing research. Research institutions like Duke, Mayo and others centers of excellence constantly pursue research to improve treatment approaches in efforts to develop more effective treatment and to reduce the burden of side effects for patients.

Understanding which patients benefit from which therapies and personalized medicine improves this experience. The Duke study sounds like a good discovery that hopefully will benefit patients (and providers). Please note that the study was conducted in the lab (in vitro) and not yet conducted in clinical studies with humans. That's when the rubber hits the road. 🙂