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Hot flashes more than a year after ending treatment

Prostate Cancer | Last Active: Oct 30 5:26pm | Replies (28)
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@jbnewby1313 Edward

Duke has recently published a study that says the use of hormone treatment as practiced for the last 20 years is backwards with normal testosterone levels best for aggressive cancer and low testosterone best for less aggressive cancer.
Most doctors are ignoring this new revelation and are still following the practices developed 20 years ago. If Duke is right, then hormone treatment should only be used for low levels of cancer.

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Replies to "@jbnewby1313 Edward Duke has recently published a study that says the use of hormone treatment as..."
jbnewby1313 | @jbnewby1313 | Oct 30 2:27pm

@pesquallie
Will you please share the study or the name of the study? Thanks

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jeff Marchi | @jeffmarc | Oct 30 3:06pm

@pesquallie

While this test does show that 1/3 of men could benefit from NOT having 24 weeks of ADT the biomarker that can tell who that one third are, is still not available. 2/3 of men in the study did benefit from ADT for 24 months.

“About two-thirds of the men had a positive biomarker, meaning that they benefited from the two years of hormonal therapy,” said Andrew Armstrong, MD, director of research for the DCI Center for Prostate and Urologic Cancers. “But one third of the men did not—they had no added risk of cancer spreading or coming back. That would save a third of all high-risk men that extra 18 months of hormonal therapy.”

We sought to develop a biomarker using tissue that could identify patients that really need those two years of hormonal therapy, or patients that could have excellent outcomes and not have to spend two years on hormonal therapy,” Armstrong said.

While the development and validation of the biomarker is complete, the team is now moving toward commercialization and creating a product that can be approved and used by doctors.

More information is available in this link
https://www.dukecancerinstitute.org/blogs/ai-tool-may-help-some-prostate-cancer-patients-avoid-hormone-therapy

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