Replies to I have paroxysmal hemicrania and have done for 20 years. It is controlled by indomethacin but…

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Neuropathy | Last Active: Oct 31, 2025 | Replies (4)

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@jodemeacham

I have paroxysmal hemicrania and have done for 20 years. It is controlled by indomethacin but I can’t take it now due to ulcers. The only time I have been in remission is when I was pregnant. Is there any research to show they are hormone related?

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Replies to "I have paroxysmal hemicrania and have done for 20 years. It is controlled by indomethacin but..."

John, Volunteer Mentor | @johnbishop | Oct 30, 2025

Welcome @jodemeacham, Sorry to hear that you are unable to use the standard treatment for paroxysmal hemicrania due to ulcers. I did find a few references that mention a hormone connection that might be helpful.

-- Facial paroxysmal hemicrania associated with the menstrual cycle:
https://journals.sagepub.com/doi/10.1177/2515816319857070
-- Paroxysmal Hemicrania:
https://pmc.ncbi.nlm.nih.gov/articles/PMC5909129/
-- How can you manage an indomethacin-responsive headache in someone who cannot take indomethacin?: https://pmc.ncbi.nlm.nih.gov/articles/PMC12052051/

You mentioned that you can't take the indomethacin due to ulcers. Are the ulcers a result of taking the indomethacin for a long period of time?

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