A little off the current discussion but thought I would add my experience with my wife who was diagnosed earlier this year. She has gone through 5 Leqembi infusions and luckily no major side effects. Some nausea and fatigue but otherwise she is doing good. Some have asked if anyone can tell if the infusions are helping and I have a method (not scientific by any means) to see if the infusions are helping. Early in the journey my wife and I would play backgammon. She struggled but it was good for her. I noted parts of the game she struggled with to get a baseline of where she was at. After her 4th infusion we played again so I could see how she did. She actually did better in the areas she struggled with in previous games. I've done that with other things to see how she is doing and I am very cautiously optimistic about her progress. Ultrasound was mentioned but there are two other promising trials either getting ready or has started. A drug called Trontinemab and another called AADVac1. You can read more about each of them at clinicaltrials.gov.

Good luck to all.