I'm glad you posted a note. My husband also had his 5th lequembe infusion, and so far two MRI's inbetween. We're being told before the 3rd 5th 7th and 14th infusion, they have to do an MRI to make sure they check on no problem, brain swelling or brain bleeding. To date, he's doing well; I did notice that he was tired around the 3rd or so infusion. It seems to be getting a bit better but we've had a lot going on. It's good to hear that mayo said your husband was a good candidate for the lequembe infusion. We felt we needed to do it, I was nervous but my husband optimistic, and that's a good thing. Keep me posted on how your husband does. And I"ll do the same.