← Return to ADT, maybe not? Anyone opted out of ADT?

Discussion
bob1955 avatar

ADT, maybe not? Anyone opted out of ADT?

Prostate Cancer | Last Active: 2 hours ago | Replies (83)

Comment receiving replies
Profile picture for daveslp @daveslp

I have a similar situation with Gleason 3+4 and 4+3 (intermediate unfavorable), age 74, PSMA indicating no current evidence of spread and planning SBRT 5 sessions coming up soon. Had an Artera test that indicated "low risk" and am waiting for the Decipher results which I believe will have additional useful info. I have been given the option of not having ADT and am trying to sort it all out in the next few days. So any answers to Bob1955 will be helpful to me, as well!

Jump to this post


Replies to "I have a similar situation with Gleason 3+4 and 4+3 (intermediate unfavorable), age 74, PSMA indicating..."

@daveslp
I had the same Gleason scores as you. My original treatment plan was radiation with hormone treatments. When the Decipher came back it came in at low risk not intermediate as biopsies had indicated.

So I did not have ADT or any hormone treatment. My treatment plan without the ADT came from Mayo R/O, UFHPTI R/O, and my Mayo PCP all saying the Decipher test removed that as a recommendation.

It has to be a personal decision knowing the side affects of hormone treatments. And from everything posted here on MCC there will be side affects. What I see is the degree of them. What I also see is the mental aspect of knowing you are getting a hormone shown to stop or at least hinder the growth of the cancer and will benefit regardless of radiation or RP.

For me at 76 with Heart Failure I don't think I would have done well and was glad when the recomendation was removed from my treatment plan. When my diagnosis was made I had a 3.75 PSA. Now 2.5 years later my PSa is .12

I do have to be careful as during radiation treatments I was told to stop my long distance bike riding (25 miles) as could irriate prostate. I have slowly inched my way back up to the 20 miles per hour but boy my genitals, butt are not happy I did.

@daveslp you have to make it a deceison of what is best for you. I responded as you had the same initial risk level you had intermediate. But then my Decipher came back low risk. Hopefully your Decipher will be the same low risk and that should help you decide.

I see you planning to do SBRT 5 sessions. I assume that is photon radiation. I had 30 rounds of proton radiation done at UFHPTI

@daveslp I finished 5 SBRT sessions on 3 October and got my first injection of ADT medication (Leuprolide/Camcevi) on 6 October. I'm slated for 3 years on ADT, injections each 6 months, PSA checks every 3 months. My Gleason was 4+4, along with several 4+3 and 3+4. So far I've not noticed any significant side effects to the ADT. I walk an hour a day or stationary bike 30 minutes. I also do core each day and some light weight lifting every other day. I turn 69 in December.

On the SBRT treatment, I started having extreme burning during urination after the third SBRT session, ibuprofen helped a bit, AZO did not. The burning continued until about 10 days after the final SBRT session. At present urination is only mildly uncomfortable.
Good luck with all of this.