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Does puncturing the prostate capsule spread cancer?
Prostate Cancer | Last Active: Oct 30, 2025 | Replies (9)Comment receiving replies
I just read that short paper. It's a paper on reviewing other papers. No description of the method used on the original studies at all. Granted, I didn't read all the supporting papers.
My question would be "How could you possibly know how many incidents of seeding occurred?" What did they use to deterimine this?
I do still agree with the conclusion statement "we do not advocate avoidance of biopsies as the benefits of appropriate cancer diagnosis and management outweigh any potential risks from seeding." I think that's valid until there is a way to say with some greater confidence when this does or does not happen.
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@web265 That’s what “literature searches” do; they search for all literature mentioning (in this case) prostate cancer needle track seeding.
From those literature they have insight into “…incidence, clinical presentation, risk factors, type of needle used, transrectal vs transperineal approach, as well as tumour grade and stage.”
They even provided links to the literature they searched so that anyone interested in further details could investigate for themselves (if wanting to know for example, when this does or does not happen), though that was not the purpose of this literature review.
What was more interesting to me was their reporting that “… In most cases (33), seeding was reported after transperineal biopsy of the prostate, while 9 cases occurred after transrectal biopsy.” This at a time when transperineal biopsies were relatively rare.