You say...""I have read quite a bit about success Dr. Eugene Kwon has had using this treatment combination. Your thoughts would be appreciated."

I can relate my experience albeit keep in mind two things, study of one, it's dated...

After surgery, BCR then SRT, my PSA continued to rise. My urologist and one who I sought a 2nd opinion, wanted to put me on ADT monotherapy, Lupron, continuous...

The STAMPEDE and CHAARTED trials were wrapping up. I reviewed those and thought, well, your clinical data isn't an exact fit but given my PSADT and PSAV, it wouldn't be long.

I remember my urologist saying "Kevin, I don't like what your PSA is doing...!" I'm thinking you don't, how do you think I feel!

I digress...I saw sone articles about Kwon, his aggressive approach, so off I went to Rochester. Kwon had the C11 Choline scan done, based on that, my clinical history and current clinical data, he recommended I do triplet therapy;

24 months Lupron
Six cycles Taxotere
WPLN radiation.

He held the ARI in reserve, waiting to see how I responded to the Lupron and Taxotere..

I finished the treatment early, coming off Lupron at 18 months vice 24. We did not add the ARI since my PSA dropped to undetectable in the first three months and stayed there.

How was the chemotherapy...tolerable, usual side effects, fatigue, nails, hair, taste...

The first 24-48 hours after infusion were ok given the drugs that go in before infusion to prevent nausea, don't want to vomit that Taxotere!

The next 3-5 days would be the crash then the next 10-14 would be tolerable and then we'd start the cycle all over again. I worked, would go to the gym, traveled once, went to see a Willie Nelson concert....I did take naps...

As @jeffmarc days, today you more options than I did in January 2017, discuss with your medical team.

My version of triplet therapy brought an almost five year hiatus from treatment.

High risk PCa generally requires more aggressive treatment decisions.

Kevin