PSMA PET Scans...some interesting info

Posted by callibaetis @callibaetis, Oct 16 10:13am

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Profile picture for Ali @muhammadali1951

@brianjarvis
PSA: 12.800
Fee PSA: 1.160
% of free PSA: 9.06
Free PSA total PSA ratio: 0.090

Prostate Biopsy:
Acinar adenocarcinoma prostate
Gleason score: 4+4=8, Grade group: 4
Cribriform pattern present
The tumour involves the right lobe
Perineural invasion identified

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@muhammadali1951 The PSMA PET scan will provide more numbers (called SUVmax scores) which will give more insight into the aggressiveness of the disease,

For now - your prostate cancer (Grade 4 out of 5) - the NCCN guidelines recommend either RP or RT+ADT. (See attached chart.)
The cribriform pattern is an indicator of possibly more advanced disease.
You’ll need to discuss with your doctor whether RT+ADT or RP will work; and if you do RP, will you have to do RT+ADT anyway?

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Profile picture for brianjarvis @brianjarvis

@muhammadali1951 The PSMA PET scan will provide more numbers (called SUVmax scores) which will give more insight into the aggressiveness of the disease,

For now - your prostate cancer (Grade 4 out of 5) - the NCCN guidelines recommend either RP or RT+ADT. (See attached chart.)
The cribriform pattern is an indicator of possibly more advanced disease.
You’ll need to discuss with your doctor whether RT+ADT or RP will work; and if you do RP, will you have to do RT+ADT anyway?

Jump to this post

@brianjarvis Thank you very much.

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Profile picture for Ali @muhammadali1951

@brianjarvis Thank you very much.

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@muhammadali1951 You'll almost cetainly go on hormone therapy. Your first big decision will be radiation vs surgery. If the imaging shows the cancer has spread, it will probably be radiation; if there's no detectable spread, you might have surgery as an option, with the caveat that you'll still need radiation later if it turns out some of the cancer had escaped the prostate but wasn't detectable yet. Surgery and radiation have comparable overall-survival stats.

No point worrying past that yet. Just rest assured that there are many good treatment options available, no matter what your situation ends up being.

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Profile picture for brianjarvis @brianjarvis

@dpayton I probably would’ve had weight gain while I was on Eligard. But, my medical oncologist advised me before the first injection to start a robust resistance-training and cardio program.
So, I lifted weights 6 days/week, and also would either run 5Ks or swim laps for 35-45 minutes on alternating days. Actually lost 40 lbs (& 3 belt sizes). Hot flashes became mild warm flashes……

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@brianjarvis Hey Brian! Thanks for the response. I wish I'd been told that! haha It was recommended that I do core work. Nothing about cardio. About 3 months in on my first shot, I went to the track to run. Now, mind you before all this started I loved to jog. I got a 1/2 mile in and it felt like I ran a 10k. Is there some in Eligard that just kills the ability to run?

Glad to hear about your story. That's awesome!!

Doug

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Profile picture for VancouverIslandHiker @vancouverislandhiker

@dpayton Thankyou for those kind words dpatyon. I very much appreciate each word that you sent me. I think my numbers are OK and I think the doctors are not really too concerned about me. But that doesn't lessen my anxiety given my life experience and my father. Yes, I am thankful for all the research that has been done for the prostate cancer brotherhood. Thank you Sir for your kind words again and God bless you and your family. James from Vancouver Island .

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@vancouverislandhiker We're pretty similar in terms of dads have a cancer history. Mine died of colon cancer. I personally try to laugh and smile everyday and not think about the past. We have so much to rely on going forward. We got this man! We got this!!!

Doug

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Profile picture for dpayton @dpayton

@brianjarvis Hey Brian! Thanks for the response. I wish I'd been told that! haha It was recommended that I do core work. Nothing about cardio. About 3 months in on my first shot, I went to the track to run. Now, mind you before all this started I loved to jog. I got a 1/2 mile in and it felt like I ran a 10k. Is there some in Eligard that just kills the ability to run?

Glad to hear about your story. That's awesome!!

Doug

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@dpayton Yes, the lack of energy will show up in basic home activities like running - even simple activities like yard work and gardening.
Remember that the hormone that gives you all of your male characteristics, including strength, fitness, endurance, etc, is basically being suppressed.
Your T levels are now below most women’s levels. (I refer to ADT as kryptonite. Remember on the old Superman TV shows of what Kryptonite would do to him? That’s what ADT does to men.)
Resistance-training exercise starting before starting ADT is key to getting through ADT.

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Profile picture for northoftheborder @northoftheborder

@muhammadali1951 You'll almost cetainly go on hormone therapy. Your first big decision will be radiation vs surgery. If the imaging shows the cancer has spread, it will probably be radiation; if there's no detectable spread, you might have surgery as an option, with the caveat that you'll still need radiation later if it turns out some of the cancer had escaped the prostate but wasn't detectable yet. Surgery and radiation have comparable overall-survival stats.

No point worrying past that yet. Just rest assured that there are many good treatment options available, no matter what your situation ends up being.

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@northoftheborder Thank you. That's very reassuring. Thank you again.

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