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wpg215 avatar

time to decide and I'm stuck....

Prostate Cancer | Last Active: Nov 3 8:05pm | Replies (58)

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@brianjarvis My Gleason is 4+3, like yours. I just had an ArteraAI test, recently approved by NCCN, and it indicated that ADT would NOT improve my chances of a successful outcome in any significant way. In other words, it would be a waste of time, resources, and hot flashes to add ADT therapy. I would have forgone radiation just to avoid ADT, but now that is not a concern. Almost makes my decision harder...now I'm truly between RP and RT.

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Replies to "@brianjarvis My Gleason is 4+3, like yours. I just had an ArteraAI test, recently approved by..."

@jesse65

Do you have any IDC or cribriform glands in you pathology report ?

If yes, according to some research papers and according to both RO and the urologist that my husband saw, RP might give you better chance for PC eradication.

@jesse65 So, with success rates comparing surgery with radiation being statistically equivalent no matter what treatment chosen (https://www.nejm.org/doi/full/10.1056/NEJMoa2214122), looks like your decision goes back to just side-effects and quality-of-life (or as that paper concludes, “… the choice of therapy involves weighing trade-offs between benefits and harms associated with treatments for localized prostate cancer.”).