← Return to Update Evenity followed by 2 years of alendronate

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hikernurse,

I’m sorry to hear about the unanticipated BMD loss while on Fosamax. A CTX of 361 with the accompanying BMD loss suggests your bone turnover isn’t fully suppressed. If you could, please share what your CTX shows when your new labs come back.

While switching to a stronger antiresorptive such as zoledronic acid or Prolia would likely be recommended, in your situation I’d lean more toward an anabolic. With the upcoming bunion surgery and a modest turnover state, a course of Tymlos or Forteo could help re-stimulate bone formation and protect against the BMD loss that often happens during periods of reduced mobility.

Starting Tymlos or Forteo would also give you a period of time to think over the next step - which antiresorptive to use afterward to protect the gains. This would also open the door for another round of Evenity should you need it.

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Replies to "hikernurse, I’m sorry to hear about the unanticipated BMD loss while on Fosamax. A CTX of..."

@mayblin
Thank you so much for your kind guidance Malin my husband who is a retired MD wholeheartedly agrees with you so I believe I will try to contact my endocrinologist through the portal and try to get it started ASAP. My concern is the upcoming surgery and I’d like to have something on board that is helping me with my bones and through that period of immobility many many thanks. I guess I don’t understand why the eluate held my gains and even increase them for a year but in the second year they did not and this is a true test to why you get a DEXA every year and not every two years I basically had to beg for one every year, and I would encourage everybody to push for that thank you

@mayblin
I am confused by your use of the term 'bone turnover rate.' I had thought 'turnover' included both removal of old bone and formation of new bone.

Why would 'fully' suppressing 'bone turnover' be a good thing?

@mayblin
CTX is 293…… Haven’t seen endo yet but brief portal
conversations have him leaning towards another course of evenity. Appt isn’t until nov 6 and bunion surgery nov 14. Podiatrist trying to call him for guidance.