@mlpults - Hi! I also looked up Indomethacin and did not like what i read….I don’t want to take anything daily plus too many side effects … it also said not to lay down for 15 minutes after taking the pill so I guess you don’t take it at night??? and it’s most common side effects are everything that I despise such as nausea, vomiting, diarrhea, constipation, heartburn stomach, discomfort, and indigestion.. everything I avoid if possible. I guess we all find what works for us. Fiorcet may stay in the system longer, but I have absolutely no side effects and I only take it when I have my head pain.