My daughter went to Mayo Scottsdale. She was diagnosed with mast cell activation, that was the underlying cause of the SIBO. Since she has been on the med, she has not had SIBO. I can't remember how many years it has been. At least 6, maybe 8. A neurologist diagnosed her with POTS and Ehler's Danlos as well. She takes a lot of meds. The mast cell med is Cromolyn Sodium. The doctor was Brent Goodman. It looks like he is no longer at Mayo, but it also looks like he still has an association with them. She lives in VA. Her mast cell doctor is an allergist. If you have recurring SIBO you might want to investigate mast cell activation.