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DiscussionPancreatic Cancer Recurrence after Whipple
Pancreatic Cancer | Last Active: 5 days ago | Replies (114)Comment receiving replies
Replies to "@stageivsurvivor Wanting to ask how you are doing now - hope just the same as in..."
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@katieliz Doing better than ever! Was at the American Academy of Clinical Research (AACR) special meeting in Boston on pancreatic cancer research 9/27 to 10/1. Flew to Switzerland 10/2 for hiking in the Swiss Alps. Flew home on 10/19 and have been in Philadelphia 10/21 at the Eastern Comprehensive Oncology Group-Academy of Clinical Radiology and Imaging Network ECOG-ACRIN) semi-annual meeting. I serve on its GI Cancers Committee as a research patient advocate providing input on clinical trials development from the patient standpoint.
I have exceeded 13 years survival and considered cured. The mechanism that resulted in cure was the amount and duration of Folfirinox I was able to tolerate that caused conversion of immunologically cold tumors to immunologically hot tumors where they expressed neoantigens making them recognizable by the immune system. This led to TCR lymphocytes and CD8+ T memory cells addressing any minimal residual disease leading to cure.