@lilyann Hypersensitivity to inactive ingredients
The inactive ingredients (excipients) in different brands of levothyroxine can cause an allergic or hypersensitivity reaction, leading to a rash and itching. Some people with this reaction found their symptoms resolved after switching to a different formulation, such as a liquid or a brand with different excipients.
Itching from a change in thyroid levels
Itching can also be a sign of hyperthyroidism, a condition caused by having too much thyroid hormone. This may occur if your levothyroxine dose is too high
Tirosint capsules do not contain fillers such as gluten, lactose, or dyes, which are often found in tablet forms of levothyroxine. This makes it a suitable alternative for patients with allergies, sensitivities, or absorption issues.

Tirosint has a very minimal list of inactive ingredients:
Tirosint gel capsules: The liquid form of levothyroxine in gel capsules contains just three inactive ingredients: gelatin, glycerin, and water.
Tirosint-SOL liquid: The single-dose ampules are even more minimalist, containing only glycerol and water along with the active ingredient
The "clean" formulation of Tirosint and Tirosint-SOL can be beneficial for certain patients for several reasons:
Fewer allergens: A common reason for intolerance to standard levothyroxine tablets is an allergy or sensitivity to the fillers and binders they contain, such as lactose or cornstarch.