The symptoms of TIF-1 feel and look very familiar. I had a persistent skin rash from 2020 until March 2025. It's improved significantly since then, but my muscle weakness remains. However, I was diagnosed with Stevens-Johnson Syndrome (SJS).

Initially, methotrexate helped reduce the skin lesions, but I experienced side effects such as hair loss and excessive bleeding.

Medications that may trigger TIF-1 include corticosteroids, azathioprine, methotrexate, mycophenolate mofetil, leflunomide, tacrolimus, immunoglobulins, and rituximab.

By the way, was your husband ever checked for APS (Antiphospholipid Syndrome)?