I have Crohn’s Disease along with really bad case of diverticulosis. Right now I’m off of biologics due to having too much illness—Influenza A, bibasilar pneumonia, and pneumonia in the right base— within about 18 months. Entyvio worked well for about 5 years. Then I went on Stelara which almost did me in. My main complaints now are pain in lower left quadrant almost everyday, chronic constipation, and chronic fatigue. My GI doctor put me on Trulance, but its action is unpredictable. I really don’t know where to turn to next. My GI doctor doesn’t seem to be impressed at all, but I know I felt great when I was on Entyvio. It’s very frustrating. I would love to travel again.